Sex-differential non-specific effects of adjuvanted and non-adjuvanted rabies vaccines versus placebo on all-cause mortality in dogs (NERVE-Dog study): a study protocol for a randomized controlled trial with a nested case–control study

Sex-differential non-specific effects of adjuvanted and non-adjuvanted rabies vaccines versus placebo on all-cause mortality in dogs (NERVE-Dog study): a study protocol for a randomized controlled trial with a nested case–control study

Abstract Background It has been proposed that childhood vaccines in high-mortality populations may have substantial impacts on mortality rates that are not explained by the prevention of targeted diseases, nor conversely by typical expected adverse reactions to the vaccines, and that these non-speci...

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Bibliographic Details
Main Authors: Darryn L. Knobel, Anne Conan, Felix N. Toka, Sintayehu M. Arega, Charles Byaruhanga, Eric Ogola, Erick M. O. Muok, Jan E. Crafford, Andrew L. Leisewitz, Melvyn Quan, Mary Anna Thrall
Format: Article
Language:English
Published: BMC 2022-10-01
Series:BMC Veterinary Research
Subjects:
Non-specific effects
Vaccine
Sex
Mortality
Rabies
Dogs
Online Access:https://doi.org/10.1186/s12917-022-03455-6

Internet

https://doi.org/10.1186/s12917-022-03455-6

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