Calcium signaling mediates proliferation of the precursor cells that give rise to the ciliated left-right organizer in the zebrafish embryo

Calcium signaling mediates proliferation of the precursor cells that give rise to the ciliated left-right organizer in the zebrafish embryo

Several of our internal organs, including heart, lungs, stomach, and spleen, develop asymmetrically along the left-right (LR) body axis. Errors in establishing LR asymmetry, or laterality, of internal organs during early embryonic development can result in birth defects. In several vertebrates—inclu...

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Bibliographic Details
Main Authors: Osama Abdel-Razek, Amanda Marzouk, Madison MacKinnon, Edward T. Guy, Sonny A. Pohar, Emily Zhushma, Junjie Liu, Isabel Sia, Jason J. Gokey, Hwee Goon Tay, Jeffrey D. Amack
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-12-01
Series:Frontiers in Molecular Biosciences
Subjects:
embryonic development
organ laterality
birth defects
left-right organizer
cilia
Ca2+ signaling
Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2023.1292076/full

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https://www.frontiersin.org/articles/10.3389/fmolb.2023.1292076/full

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