Local mitochondrial replication in the periphery of neurons requires the eEF1A1 protein and thetranslation of nuclear-encoded proteins

Local mitochondrial replication in the periphery of neurons requires the eEF1A1 protein and thetranslation of nuclear-encoded proteins

Summary: In neurons, it is commonly assumed that mitochondrial replication only occurs in the cell body, after which the mitochondria must travel to the neuron’s periphery. However, while mitochondrial DNA replication has been observed to occur away from the cell body, the specific mechanisms involv...

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Bibliographic Details
Main Authors: Carlos Cardanho-Ramos, Rúben Alves Simões, Yi-Zhi Wang, Andreia Faria-Pereira, Ewa Bomba-Warczak, Katleen Craessaerts, Marco Spinazzi, Jeffrey N. Savas, Vanessa A. Morais
Format: Article
Language:English
Published: Elsevier 2024-04-01
Series:iScience
Subjects:
Biochemistry
Biological sciences
Cellular neuroscience
Molecular neuroscience
Natural sciences
Neuroscience
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004224003572

Internet

http://www.sciencedirect.com/science/article/pii/S2589004224003572

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