Trastuzumab-Mediated Cardiotoxicity and Its Preventive Intervention by Zingerone through Antioxidant and Inflammatory Pathway in Rats

Trastuzumab-Mediated Cardiotoxicity and Its Preventive Intervention by Zingerone through Antioxidant and Inflammatory Pathway in Rats

Trastuzumab (TZB) is a new medicine, used to treat cancers of the breast and stomach. However, the cardiotoxic potential of this drug edges out its clinical advantages. The present study was designed to find out the effect of zingerone against trastuzumab-mediated cardiotoxicity in rats. In this stu...

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Bibliographic Details
Main Authors: Gyas Khan, Mohammad Firoz Alam, Saeed Alshahrani, Yosif Almoshari, Abdulmajeed M. Jali, Saud Alqahtani, Mohammad Khalid, Shehla Nasar Mir Najib Ullah, Tarique Anwer
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:Journal of Personalized Medicine
Subjects:
zingerone
trastuzumab
cardiotoxicity
interleukin
IL-2 and TNF-α
histopathology
Online Access:https://www.mdpi.com/2075-4426/13/5/750

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https://www.mdpi.com/2075-4426/13/5/750

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