Emergence of RAS mutations in patients with metastatic colorectal cancer receiving cetuximab-based treatment: a study protocol

Abstract Background In the management of patients with RAS wild-type metastatic colorectal cancer (mCRC), anti-epidermal growth factor receptor (EGFR) therapies have demonstrated a clinical benefit, with longer survival. However, the correlation between the emergence of circulating RAS mutations and...

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Bibliographic Details
Main Authors: Shang-Hung Chen, Hsiang-Lin Tsai, Jeng-Kai Jiang, Yung-Chuan Sung, Ching-Wen Huang, Yu-Min Yeh, Li-Tzong Chen, Jaw-Yuan Wang
Format: Article
Language:English
Published: BMC 2019-06-01
Series:BMC Cancer
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12885-019-5826-7