Pan-cancer screening by circulating tumor DNA (ctDNA) – recent breakthroughs and chronic pitfalls

Pan-cancer screening by circulating tumor DNA (ctDNA) – recent breakthroughs and chronic pitfalls

Early detection is crucial for optimal treatment and prognosis of cancer. New approaches for pan-cancer screening comprise the comprehensive characterization of circulating tumor DNA (ctDNA) in plasma by next generation sequencing and molecular profiling of mutations and methylation patterns, as wel...

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Bibliographic Details
Main Authors: Holdenrieder Stefan, Ungerer Vida, Oberhofer Angela, Bronkhorst Abel Jacobus
Format: Article
Language:English
Published: De Gruyter 2022-08-01
Series:Journal of Laboratory Medicine
Subjects:
cancer
ctdna
early detection
fragment analysis
liquid profiling
methylation
mutations
next generation sequencing
screening
Online Access:https://doi.org/10.1515/labmed-2022-0029

Internet

https://doi.org/10.1515/labmed-2022-0029

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