Long-term follow-up of a randomized controlled trial of choline for neurodevelopment in fetal alcohol spectrum disorder: corpus callosum white matter microstructure and neurocognitive outcomes

Long-term follow-up of a randomized controlled trial of choline for neurodevelopment in fetal alcohol spectrum disorder: corpus callosum white matter microstructure and neurocognitive outcomes

Abstract Background Fetal alcohol spectrum disorder (FASD) is a lifelong condition. Early interventions targeting core neurocognitive deficits have the potential to confer long-term neurodevelopmental benefits. Time-targeted choline supplementation is one such intervention that has been shown to pro...

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Bibliographic Details
Main Authors: Blake A. Gimbel, Mary E. Anthony, Abigail M. Ernst, Donovan J. Roediger, Erik de Water, Judith K. Eckerle, Christopher J. Boys, Joshua P. Radke, Bryon A. Mueller, Anita J. Fuglestad, Steven H. Zeisel, Michael K. Georgieff, Jeffrey R. Wozniak
Format: Article
Language:English
Published: BMC 2022-12-01
Series:Journal of Neurodevelopmental Disorders
Subjects:
Fetal alcohol spectrum disorders
Choline
Cognition
Longitudinal studies
Diffusion MRI
Neurite orientation dispersion and density imaging
Online Access:https://doi.org/10.1186/s11689-022-09470-w

Internet

https://doi.org/10.1186/s11689-022-09470-w

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