A novel TPD52L2-ROS1 gene fusion expanding the molecular alterations in inflammatory myofibroblastic tumor: case report and literature review

A novel TPD52L2-ROS1 gene fusion expanding the molecular alterations in inflammatory myofibroblastic tumor: case report and literature review

Abstract Background Inflammatory myofibroblastic tumor (IMT) is a distinctive tumor composed of spindle cells accompanied by mixed inflammatory cells, and immunohistochemical positivity for ALK (anaplastic lymphoma kinase protein) can be detected in half of IMTs. The diagnosis of ALK-negative IMT co...

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Bibliographic Details
Main Authors: Xuguang Liu, Yaqi Duan, Guoping Wang, Pengcheng Zhu
Format: Article
Language:English
Published: BMC 2023-09-01
Series:Diagnostic Pathology
Subjects:
IMT
ROS1
TPD52L2
Case report
Crizotinib
Online Access:https://doi.org/10.1186/s13000-023-01382-0

Internet

https://doi.org/10.1186/s13000-023-01382-0

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