MicroRNA-nanoparticles against cancer: Opportunities and challenges for personalized medicine

Micro-RNAs (miRNAs) control gene expression at the post-transcriptional level and are widely involved in carcinogenesis, playing a role as both oncogenes and tumor suppressors. MiRNAs act as potent therapeutic weapon in cancer, but their potential therapeutic use is limited by the off-target effect...

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Bibliographic Details
Main Authors: Elisa Martino, Nunzia D’Onofrio, Camilla Anastasio, Marianna Abate, Silvia Zappavigna, Michele Caraglia, Maria Luisa Balestrieri
Format: Article
Language:English
Published: Elsevier 2023-06-01
Series:Molecular Therapy: Nucleic Acids
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S216225312300080X