Promoting Fc-Fc interactions between anti-capsular antibodies provides strong immune protection against Streptococcus pneumoniae

Promoting Fc-Fc interactions between anti-capsular antibodies provides strong immune protection against Streptococcus pneumoniae

Streptococcus pneumoniae is the leading cause of community-acquired pneumonia and an important cause of childhood mortality. Despite the introduction of successful vaccines, the global spread of both non-vaccine serotypes and antibiotic-resistant strains reinforces the development of alternative the...

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Bibliographic Details
Main Authors: Leire Aguinagalde Salazar, Maurits A den Boer, Suzanne M Castenmiller, Seline A Zwarthoff, Carla de Haas, Piet C Aerts, Frank J Beurskens, Janine Schuurman, Albert JR Heck, Kok van Kessel, Suzan HM Rooijakkers
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2023-03-01
Series:eLife
Subjects:
S. pneumoniae
monoclonal antibodies
complement system
hexamer-enhancing mutations
Online Access:https://elifesciences.org/articles/80669

Internet

https://elifesciences.org/articles/80669

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