Aberrant Expression of ACO1 in Vasculatures Parallels Progression of Idiopathic Pulmonary Fibrosis

Aberrant Expression of ACO1 in Vasculatures Parallels Progression of Idiopathic Pulmonary Fibrosis

Rationale: Idiopathic pulmonary fibrosis (IPF) is characterized by mitochondrial dysfunction. However, details about the non-mitochondrial enzymes that sustain the proliferative nature of IPF are unclear. Aconitases are a family of enzymes that sustain metabolism inside and outside mitochondria. It...

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Bibliographic Details
Main Authors: Jutaro Fukumoto, Muling Lin, Mudassir Meraj Banday, Sahebgowda Sidramagowda Patil, Sudarshan Krishnamurthy, Mason Breitzig, Ramani Soundararajan, Lakshmi Galam, Venkata Ramireddy Narala, Colleen Johns, Kapilkumar Patel, John Dunning, Richard F. Lockey, Nirmal S. Sharma, Narasaiah Kolliputi
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-07-01
Series:Frontiers in Pharmacology
Subjects:
lung injury
ACO1
IRP1
IPF
angiogenesis
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2022.890380/full

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https://www.frontiersin.org/articles/10.3389/fphar.2022.890380/full

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