Fatal enteric plexus neuropathy after one dose of ipilimumab plus nivolumab: a case report

Fatal enteric plexus neuropathy after one dose of ipilimumab plus nivolumab: a case report

Abstract Background Immune checkpoint inhibitors (ICIs) are the treatment of choice for several cancers and can be associated with remarkable clinical benefit, but can also cause serious immune-related adverse events (irAEs). Management of rare and severe irAEs is challenged by an incomplete knowled...

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Bibliographic Details
Main Authors: Jacob Appelbaum, David Wells, Joseph B. Hiatt, Gideon Steinbach, F. Marc Stewart, Hannah Thomas, Paul Nghiem, Raj P. Kapur, John A. Thompson, Shailender Bhatia
Format: Article
Language:English
Published: BMJ Publishing Group 2018-08-01
Series:Journal for ImmunoTherapy of Cancer
Subjects:
Ileus
Merkel cell
Ipilimumab
Nivolumab
Immune-related adverse events
Pseudo-obstruction
Online Access:http://link.springer.com/article/10.1186/s40425-018-0396-9

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http://link.springer.com/article/10.1186/s40425-018-0396-9

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