KMT2A/C mutations function as a potential predictive biomarker for immunotherapy in solid tumors
Abstract Epigenetic factors play important roles in tumor immunology. Histone-lysine N-methyltransferase 2 (KMT2) family genes exert histone H3 methylation, but its role in immunotherapy remains unclear. Our study is the first to investigate the correlation between KMT2 gene mutations and the clinic...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2020-12-01
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Series: | Biomarker Research |
Subjects: | |
Online Access: | https://doi.org/10.1186/s40364-020-00241-0 |