TGF-β1 Increases GDNF Production by Upregulating the Expression of GDNF and Furin in Human Granulosa-Lutein Cells

Glial cell line-derived neurotrophic factor (GDNF) is expressed at a high level in the human ovary and GDNF signaling is involved in the direct control of follicular activation and oocyte maturation. Transforming growth factor-β1 (TGF-β1) plays an important role in the regulation o...

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Bibliographic Details
Main Authors: Jingwen Yin, Hsun-Ming Chang, Yuyin Yi, Yuanqing Yao, Peter C.K. Leung
Format: Article
Language:English
Published: MDPI AG 2020-01-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/9/1/185