In Silico Methods in Antibody Design

In Silico Methods in Antibody Design

Antibody therapies with high efficiency and low toxicity are becoming one of the major approaches in antibody therapeutics. Based on high-throughput sequencing and increasing experimental structures of antibodies/antibody-antigen complexes, computational approaches can predict antibody/antigen struc...

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Bibliographic Details
Main Authors: Jun Zhao, Ruth Nussinov, Wen-Jin Wu, Buyong Ma
Format: Article
Language:English
Published: MDPI AG 2018-06-01
Series:Antibodies
Subjects:
antibody design
epitope prediction
antibody-antigen recognition
affinity maturation
immunogenicity
vaccine design
antibody stability
allosteric effect
Online Access:http://www.mdpi.com/2073-4468/7/3/22

Internet

http://www.mdpi.com/2073-4468/7/3/22

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