Evaluation of (89)Zr-labeled human anti-CD147 monoclonal antibody as a positron emission tomography probe in a mouse model of pancreatic cancer.

INTRODUCTION: Pancreatic cancer is an aggressive cancer and its prognosis remains poor. Therefore, additional effective therapy is required to augment and/or complement current therapy. CD147, high expression in pancreatic cancer, is involved in the metastatic process and is considered a good candid...

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Main Authors: Aya Sugyo, Atsushi B Tsuji, Hitomi Sudo, Kotaro Nagatsu, Mitsuru Koizumi, Yoshinori Ukai, Gene Kurosawa, Ming-Rong Zhang, Yoshikazu Kurosawa, Tsuneo Saga
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3618331?pdf=render