Evaluation of cytokine profiles related to Mycobacterium tuberculosis latent antigens using a whole-blood assay in the Philippines

Evaluation of cytokine profiles related to Mycobacterium tuberculosis latent antigens using a whole-blood assay in the Philippines

IntroductionThere is no useful method to discriminate between latent tuberculosis infection (LTBI) and active pulmonary tuberculosis (PTB). This study aimed to investigate the potential of cytokine profiles to discriminate between LTBI and active PTB using whole-blood stimulation with Mycobacterium...

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Main Authors: Ikkoh Yasuda, Naomi Ruth D. Saludar, Ana Ria Sayo, Shuichi Suzuki, Akira Yokoyama, Yuriko Ozeki, Haruka Kobayashi, Akihito Nishiyama, Sohkichi Matsumoto, Sharon E. Cox, Takeshi Tanaka, Yoshiro Yamashita
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-04-01
Series:Frontiers in Immunology
Subjects:
tuberculosis
latent tuberculosis infection
mycobacterial DNA-binding protein 1
α-crystallin
interferon-γ
tumor necrosis factor-α
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1330796/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2024.1330796/full

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