Quercetin declines plasma exposure of metoprolol tartrate in the rat model

Quercetin declines plasma exposure of metoprolol tartrate in the rat model

The study was undertaken to evaluate the effect of quercetin on the pharmacokinetics of Metoprolol tartrate. A single dose in vivo pharmacokinetic study was carried out in rat models. In this study, rats were treated with quercetin (10 mg/kg) and metoprolol tartrate (20 mg/kg) orally and blood sampl...

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Bibliographic Details
Main Authors: Siva R Challa, Venkatesh R Challa, Satheesh K Ragam
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2014-01-01
Series:Journal of Advanced Pharmaceutical Technology & Research
Subjects:
Bioavailability
metoprolol tartrate
organic cation transporter-2
p-glycoprotein
pharmacokinetics
quercetin
Online Access:http://www.japtr.org/article.asp?issn=2231-4040;year=2014;volume=5;issue=4;spage=185;epage=190;aulast=Challa

Internet

http://www.japtr.org/article.asp?issn=2231-4040;year=2014;volume=5;issue=4;spage=185;epage=190;aulast=Challa

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