Prenatal organophosphates exposure alternates the cleavage plane orientation of apical neural progenitor in developing neocortex.

Prenatal organophosphate exposure elicits long-term brain cytoarchitecture and cognitive function impairments, but the mechanism underlying the onset and development of neural progenitors remain largely unclear. Using precise positioned brain slices, we observed an alternated cleavage plane bias tha...

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Bibliographic Details
Main Authors: Xiao-Ping Chen, Wei-Feng Chen, Da-Wei Wang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3989278?pdf=render