Cytolytic circumsporozoite-specific memory CD4+ T cell clones are expanded during Plasmodium falciparum infection

Cytolytic circumsporozoite-specific memory CD4+ T cell clones are expanded during Plasmodium falciparum infection

Abstract Clinical immunity against Plasmodium falciparum infection develops in residents of malaria endemic regions, manifesting in reduced clinical symptoms during infection and in protection against severe disease but the mechanisms are not fully understood. Here, we compare the cellular and humor...

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Bibliographic Details
Main Authors: Raquel Furtado, Mahinder Paul, Jinghang Zhang, Joowhan Sung, Paul Karell, Ryung S. Kim, Sophie Caillat-Zucman, Li Liang, Philip Felgner, Andy Bauleni, Syze Gama, Andrea Buchwald, Terrie Taylor, Karl Seydel, Miriam Laufer, Fabien Delahaye, Johanna P. Daily, Grégoire Lauvau
Format: Article
Language:English
Published: Nature Portfolio 2023-11-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-43376-y

Internet

https://doi.org/10.1038/s41467-023-43376-y

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