The Mutational Landscape of Early-Onset Breast Cancer: A Next-Generation Sequencing Analysis

The Mutational Landscape of Early-Onset Breast Cancer: A Next-Generation Sequencing Analysis

BackgroundAround 5%–7% of breast cancer cases are diagnosed in women younger than 40, making it the leading cause of female cancer in the 25- to 39-year-old age group. Unfortunately, young age at diagnosis is linked to a more aggressive tumor biology and a worse clinical outcome. The identification...

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Bibliographic Details
Main Authors: Angeliki Andrikopoulou, Spyridoula Chatzinikolaou, Ilias Kyriopoulos, Garyfalia Bletsa, Maria Kaparelou, Michalis Liontos, Meletios-Athanasios Dimopoulos, Flora Zagouri
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-01-01
Series:Frontiers in Oncology
Subjects:
NGS
breast cancer
early-onset
genetic testing
young women
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.797505/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2021.797505/full

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