Benzo(a)pyrene and cardiovascular diseases: An overview of pre-clinical studies focused on the underlying molecular mechanism

Benzo(a)pyrene and cardiovascular diseases: An overview of pre-clinical studies focused on the underlying molecular mechanism

Benzo(a)pyrene (BaP) is a highly toxic and carcinogenic polycyclic aromatic hydrocarbon (PAH) whose toxicological effects in the vessel-wall cells have been recognized. Many lines of evidence suggest that tobacco smoking and foodborne BaP exposure play a pivotal role in the dysfunctions of vessel-wa...

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Bibliographic Details
Main Authors: Chenghao Fu, Yuemin Li, Hao Xi, Zemiao Niu, Ning Chen, Rong Wang, Yonghuan Yan, Xiaoruo Gan, Mengtian Wang, Wei Zhang, Yan Zhang, Pin Lv
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-08-01
Series:Frontiers in Nutrition
Subjects:
Benzo(a)pyrene
cardiovascular diseases
AhR
oxidative stress
inflammation
genotoxicity
Online Access:https://www.frontiersin.org/articles/10.3389/fnut.2022.978475/full

Internet

https://www.frontiersin.org/articles/10.3389/fnut.2022.978475/full

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