Quantifying the role of population subdivision in evolution on rugged fitness landscapes.

Natural selection drives populations towards higher fitness, but crossing fitness valleys or plateaus may facilitate progress up a rugged fitness landscape involving epistasis. We investigate quantitatively the effect of subdividing an asexual population on the time it takes to cross a fitness valle...

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Bibliographic Details
Main Authors: Anne-Florence Bitbol, David J Schwab
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-08-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC4133052?pdf=render