The Selective NMDA Receptor GluN2B Subunit Antagonist CP-101,606 with Antidepressant Properties Modulates Cytochrome P450 Expression in the Liver

The Selective NMDA Receptor GluN2B Subunit Antagonist CP-101,606 with Antidepressant Properties Modulates Cytochrome P450 Expression in the Liver

Recent research indicates that selective NMDA receptor GluN2B subunit antagonists may become useful for the treatment of major depressive disorders. We aimed to examine in parallel the effect of the selective NMDA receptor GluN2B subunit antagonist CP-101,606 on the pituitary/serum hormone levels an...

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Bibliographic Details
Main Authors: Ewa Bromek, Anna Haduch, Marta Rysz, Joanna Jastrzębska, Renata Pukło, Olga Wójcikowska, Przemysław Jan Danek, Władysława Anna Daniel
Format: Article
Language:English
Published: MDPI AG 2021-10-01
Series:Pharmaceutics
Subjects:
CP-101,606
NMDA receptor
cytochrome P450
liver
neuroendocrine regulation
Online Access:https://www.mdpi.com/1999-4923/13/10/1643

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https://www.mdpi.com/1999-4923/13/10/1643

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