Schlafen 11 expression in human acute leukemia cells with gain-of-function mutations in the interferon-JAK signaling pathway

Summary: Schlafen11 (SLFN11) is referred to as interferon (IFN)-inducible. Based on cancer genomic databases, we identified human acute myeloid and lymphoblastic leukemia cells with gain-of-function mutations in the Janus kinase (JAK) family as exhibiting high SLFN11 expression. In these cells, the...

詳細記述

書誌詳細
主要な著者: Yasuhisa Murai, Ukhyun Jo, Junko Murai, Shinsaku Fukuda, Naoko Takebe, Yves Pommier
フォーマット: 論文
言語:English
出版事項: Elsevier 2021-10-01
シリーズ:iScience
主題:
オンライン・アクセス:http://www.sciencedirect.com/science/article/pii/S258900422101141X