Pharmacokinetics and Pharmacodynamics of Immediate- and Modified-Release Mycophenolic Acid Preparations in Healthy Beagle Dogs

Pharmacokinetics and Pharmacodynamics of Immediate- and Modified-Release Mycophenolic Acid Preparations in Healthy Beagle Dogs

Background: Mycophenolic acid (MPA) is a broad-acting immunomodulating agent that may be therapeutically beneficial for the treatment of immune-mediated diseases in canine patients.Objectives: To determine the suppressive effects of MPA on T-cell proliferation, and to assess the feasibility of a can...

Full description

Bibliographic Details
Main Authors: Michael Klotsman, Sebastien Coquery, Gayatri Sathyan, Vatsala Naageshwaran, Paddy Shivanand, Amanda J. Fairchild, Oliver A. Garden, Wayne H. Anderson
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-01-01
Series:Frontiers in Veterinary Science
Subjects:
mycophenolic acid
immunomodiilation
pharmacodynamic
canine (dog)
immune mediated haemolytic anemia
steroid sparing agents
Online Access:https://www.frontiersin.org/articles/10.3389/fvets.2020.611404/full

Internet

https://www.frontiersin.org/articles/10.3389/fvets.2020.611404/full

Similar Items