Differential Expression and Enzymatic Activity of DPPIV/CD26 Affects Migration Ability of Cervical Carcinoma Cells.

Dipeptidyl peptidase IV (DPPIV/CD26) is a transmembrane glycoprotein that inactivates or degrades some bioactive peptides and chemokines. For this reason, it regulates cell proliferation, migration and adhesion, showing its role in cancer processes. This enzyme is found mainly anchored onto the cell...

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Main Authors: Aline Beckenkamp, Júlia Biz Willig, Danielle Bertodo Santana, Jéssica Nascimento, Juliano Domiraci Paccez, Luiz Fernando Zerbini, Alessandra Nejar Bruno, Diogo André Pilger, Márcia Rosângela Wink, Andréia Buffon
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4519168?pdf=render