Long-Term Potentiation Is Increased in the CA1 Area of the Hippocampus of APPswe/ind CRND8 Mice

The present study reports changes in synaptic function and plasticity [long-term potentiation (LTP)] in a recently developed mouse model of Alzheimer's disease (CRND8 line) harboring a double amyloid precursor protein mutation (APPswe/ind). In 9-week-old preplaque transgenic (Tg) mice brain sli...

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Bibliographic Details
Main Authors: Thierry Jolas, Xue-Song Zhang, Qi Zhang, Gwendolyn Wong, Robert Del Vecchio, Lisa Gold, Tony Priestley
Format: Article
Language:English
Published: Elsevier 2002-12-01
Series:Neurobiology of Disease
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996102905577