Anti-Colorectal Cancer Effects of a Novel Camptothecin Derivative PCC0208037 <i>In Vitro</i> and <i>In Vivo</i>

Colorectal cancer is one of the most common malignancies, and the topoisomerase inhibitor irinotecan (CPT-11)-based chemotherapeutic regimen is currently the first-line treatment with impressive therapeutic efficacy. However, irinotecan has several clinically significant side effects, including diar...

Full description

Bibliographic Details
Main Authors: Min Li, Linxu Wang, Yingjie Wei, Wenyan Wang, Zongliang Liu, Aixia Zuo, Wanhui Liu, Jingwei Tian, Hongbo Wang
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Pharmaceuticals
Subjects:
Online Access:https://www.mdpi.com/1424-8247/16/1/53