Amino acid transporter SLC38A5 is a tumor promoter and a novel therapeutic target for pancreatic cancer

Amino acid transporter SLC38A5 is a tumor promoter and a novel therapeutic target for pancreatic cancer

Abstract Pancreatic ductal adenocarcinoma (PDAC) cells have a great demand for nutrients in the form of sugars, amino acids, and lipids. Particularly, amino acids are critical for cancer growth and, as intermediates, connect glucose, lipid and nucleotide metabolism. PDAC cells meet these requirement...

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Bibliographic Details
Main Authors: Tyler Sniegowski, Devaraja Rajasekaran, Souad R. Sennoune, Sukumaran Sunitha, Fang Chen, Mohamed Fokar, Sudhir Kshirsagar, P. Hemachandra Reddy, Ksenija Korac, Mosharaf Mahmud Syed, Tanima Sharker, Vadivel Ganapathy, Yangzom D. Bhutia
Format: Article
Language:English
Published: Nature Portfolio 2023-10-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-43983-1

Internet

https://doi.org/10.1038/s41598-023-43983-1

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