A Stepwise Algorithm for Linearly Combining Biomarkers under Youden Index Maximization
Combining multiple biomarkers to provide predictive models with a greater discriminatory ability is a discipline that has received attention in recent years. Choosing the probability threshold that corresponds to the highest combined marker accuracy is key in disease diagnosis. The Youden index is a...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2022-04-01
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| Series: | Mathematics |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2227-7390/10/8/1221 |