The long non-coding RNA MIR31HG regulates the senescence associated secretory phenotype
Senescence-associated secretory phenotype (SASP) involves secretion of factors such as pro-inflammatory cytokines. Here the authors show that MIR31HG regulates the expression and secretion of a subset of SASP components that induce paracrine invasion, through interaction with YBX1 and induction of I...
Main Authors: | , , , , , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2021-04-01
|
Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-021-22746-4 |