The transcriptional risk scores for kidney renal clear cell carcinoma using XGBoost and multiple omics data

Most kidney cancers are kidney renal clear cell carcinoma (KIRC) that is a main cause of cancer-related deaths. Polygenic risk score (PRS) is a weighted linear combination of phenotypic related alleles on the genome that can be used to assess KIRC risk. However, standalone SNP data as input to the P...

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Bibliographic Details
Main Authors: Xiaoyu Hou, Baoshan Ma, Ming Liu, Yuxuan Zhao, Bingjie Chai, Jianqiao Pan, Pengcheng Wang, Di Li, Shuxin Liu, Fengju Song
Format: Article
Language:English
Published: AIMS Press 2023-05-01
Series:Mathematical Biosciences and Engineering
Subjects:
Online Access:https://www.aimspress.com/article/doi/10.3934/mbe.2023519?viewType=HTML