mRNA expression and antilipolytic role of phosphodiesterase 4 in rat adipocytes in vitro

Adipocyte lipolysis is dependent on an increase in the intracellular concentration of cAMP. Intracellular phosphodiesterases (PDEs) hydrolyze cAMP and limit stimulation of lipolysis. In the present study, the mRNA expression of PDE4 subtypes and the antilipolytic role of PDE4 in rat adipocytes were...

Full description

Bibliographic Details
Main Authors: Wang Hong, Neilé K. Edens
Format: Article
Language:English
Published: Elsevier 2007-05-01
Series:Journal of Lipid Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520435564