Changes in Cyclin D1, cdk4, and Their Associated Molecules in Ischemic Pyramidal Neurons in Gerbil Hippocampus after Transient Ischemia and Neuroprotective Effects of Ischemic Preconditioning by Keeping the Molecules in the Ischemic Neurons

Changes in Cyclin D1, cdk4, and Their Associated Molecules in Ischemic Pyramidal Neurons in Gerbil Hippocampus after Transient Ischemia and Neuroprotective Effects of Ischemic Preconditioning by Keeping the Molecules in the Ischemic Neurons

Inadequate activation of cell cycle proteins including cyclin D1 and cdk4 is involved in neuronal cell death induced by diverse pathological stresses, including transient global brain ischemia. The neuroprotective effect of ischemic preconditioning is well-established, but the underlying mechanism i...

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Bibliographic Details
Main Authors: Tae-Kyeong Lee, Dae Won Kim, Jae-Chul Lee, Cheol Woo Park, Hyejin Sim, Ji Hyeon Ahn, Joon Ha Park, Myoung Cheol Shin, Jun Hwi Cho, Choong-Hyun Lee, Moo-Ho Won, Soo Young Choi
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Biology
Subjects:
ischemic preconditioning
cyclin D1/cdk4 signals
transient global ischemia
hippocampus
pyramidal cells
gerbil
Online Access:https://www.mdpi.com/2079-7737/10/8/719

Internet

https://www.mdpi.com/2079-7737/10/8/719

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