Betel Nut Arecoline Induces Different Phases of Growth Arrest between Normal and Cancerous Prostate Cells through the Reactive Oxygen Species Pathway

Betel Nut Arecoline Induces Different Phases of Growth Arrest between Normal and Cancerous Prostate Cells through the Reactive Oxygen Species Pathway

Prostate cancer (PCa) is a reproductive system cancer in elderly men. We investigated the effects of betel nut arecoline on the growth of normal and cancerous prostate cells. Normal RWPE-1 prostate epithelial cells, androgen-independent PC-3 PCa cells, and androgen-dependent LNCaP PCa cells were use...

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Bibliographic Details
Main Authors: Li-Jane Shih, Jia-Yu Wang, Jing-Yao Jheng, An-Ci Siao, Yen-Yue Lin, Yi-Wei Tsuei, Yow-Chii Kuo, Chih-Pin Chuu, Yung-Hsi Kao
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:International Journal of Molecular Sciences
Subjects:
areca nut
prostate cancer
cell cycle
cyclin
cyclin-dependent kinase
p21
Online Access:https://www.mdpi.com/1422-0067/21/23/9219

Internet

https://www.mdpi.com/1422-0067/21/23/9219

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