Expression of TNFR1, VEGFA, CD147 and MCT1 as early biomarkers of diabetes complications and the impact of aging on this profile

Abstract Hyperglycemia leads to microvascular lesions in various tissues. In diabetic nephropathy—DN, alterations in usual markers reflect an already installed disease. The study of new biomarkers for the early detection of diabetic complications can bring new prevention perspectives. Rats were divi...

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Bibliographic Details
Main Authors: Joyce Regina Santos Raimundo, Beatriz da Costa Aguiar Alves, Jéssica Freitas Araujo Encinas, Andressa Moreira Siqueira, Katharyna Cardoso de Gois, Matheus Moreira Perez, Giuliana Petri, José Francisco Ramos dos Santos, Fernando Luiz Affonso Fonseca, Glaucia Luciano da Veiga
Format: Article
Language:English
Published: Nature Portfolio 2023-10-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-41061-0