On the fluorescence enhancement of arch neuronal optogenetic reporters

On the fluorescence enhancement of arch neuronal optogenetic reporters

Arch-3 rhodopsin variants are common fluorescent reporters of neuronal activity. Here, the authors show with quantum chemical modelling that a set of these proteins reveals a direct proportionality between their observed fluorescence intensity and the stability of an exotic excited-state diradical i...

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Bibliographic Details
Main Authors: Leonardo Barneschi, Emanuele Marsili, Laura Pedraza-González, Daniele Padula, Luca De Vico, Danil Kaliakin, Alejandro Blanco-González, Nicolas Ferré, Miquel Huix-Rotllant, Michael Filatov, Massimo Olivucci
Format: Article
Language:English
Published: Nature Portfolio 2022-10-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-022-33993-4

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https://doi.org/10.1038/s41467-022-33993-4

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