Periostin associates with Notch1 precursor to maintain Notch1 expression under a stress condition in mouse cells.

BACKGROUND: Matricellular proteins, including periostin, modulate cell-matrix interactions and cell functions by acting outside of cells. METHODS AND FINDINGS: In this study, however, we reported that periostin physically associates with the Notch1 precursor at its EGF repeats in the inside of cells...

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Bibliographic Details
Main Authors: Hideyuki Tanabe, Issei Takayama, Takashi Nishiyama, Masashi Shimazaki, Isao Kii, Minqi Li, Norio Amizuka, Ken-ichi Katsube, Akira Kudo
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2923609?pdf=render