Chondroitin sulfate functionalized palmitic acid and cysteine cografted-quaternized chitosan for CD44 and gut microbiota dual-targeted delivery of curcumin

Chondroitin sulfate functionalized palmitic acid and cysteine cografted-quaternized chitosan for CD44 and gut microbiota dual-targeted delivery of curcumin

Curcumin (CUR) has a regulatory effect on the gut microbiota (GM), and its significant anti-inflammatory properties make it a research hotspot for inflammatory bowel disease (IBD) treatment. However, the low bioavailability and poor pharmacokinetic properties of CUR limit its practical application....

Full description

Bibliographic Details
Main Authors: Yinzhuo Xie, Wei Xu, Zheng Jin, Kai Zhao
Format: Article
Language:English
Published: Elsevier 2023-06-01
Series:Materials Today Bio
Subjects:
Curcumin
Inflammatory bowel disease
Mucoadhesive nanoparticles
CD44 glycoprotein
Targeted delivery
Gut microbiota
Online Access:http://www.sciencedirect.com/science/article/pii/S2590006423000777

Internet

http://www.sciencedirect.com/science/article/pii/S2590006423000777

Similar Items