Large-scale proteomics analysis of five brain regions from Parkinson’s disease patients with a GBA1 mutation

Large-scale proteomics analysis of five brain regions from Parkinson’s disease patients with a GBA1 mutation

Abstract Despite being the second most common neurodegenerative disorder, little is known about Parkinson’s disease (PD) pathogenesis. A number of genetic factors predispose towards PD, among them mutations in GBA1, which encodes the lysosomal enzyme acid-β-glucosidase. We now perform non-targeted,...

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Bibliographic Details
Main Authors: Shani Blumenreich, Tamar Nehushtan, Meital Kupervaser, Tali Shalit, Alexandra Gabashvili, Tammar Joseph, Ivan Milenkovic, John Hardy, Anthony H. Futerman
Format: Article
Language:English
Published: Nature Portfolio 2024-02-01
Series:npj Parkinson's Disease
Online Access:https://doi.org/10.1038/s41531-024-00645-x

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https://doi.org/10.1038/s41531-024-00645-x

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