Genetically determined susceptibility to neurodegeneration is associated with expression of inflammatory genes

Genetically determined susceptibility to neurodegeneration is associated with expression of inflammatory genes

Axonal damage, a core feature of neurological diseases, induces a retrograde reaction in neurons and surrounding glia. We determined transcriptional profiles of this reaction using Affymetrix oligonucleotide arrays. Gene expression was examined in spinal cord tissue prior to injury and following ven...

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Bibliographic Details
Main Authors: Maria Swanberg, Kristina Duvefelt, Margarita Diez, Jan Hillert, Tomas Olsson, Fredrik Piehl, Olle Lidman
Format: Article
Language:English
Published: Elsevier 2006-10-01
Series:Neurobiology of Disease
Subjects:
Axotomy
Motoneuron
Neurodegeneration
Inflammation
Gene expression
Genetic
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996106001355

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http://www.sciencedirect.com/science/article/pii/S0969996106001355

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