Genetically determined susceptibility to neurodegeneration is associated with expression of inflammatory genes
Axonal damage, a core feature of neurological diseases, induces a retrograde reaction in neurons and surrounding glia. We determined transcriptional profiles of this reaction using Affymetrix oligonucleotide arrays. Gene expression was examined in spinal cord tissue prior to injury and following ven...
Main Authors: | Maria Swanberg, Kristina Duvefelt, Margarita Diez, Jan Hillert, Tomas Olsson, Fredrik Piehl, Olle Lidman |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2006-10-01
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Series: | Neurobiology of Disease |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S0969996106001355 |
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