Examination of Longitudinal Alterations in Alzheimer’s Disease-Related Neurogenesis in an APP/PS1 Transgenic Mouse Model, and the Effects of P33, a Putative Neuroprotective Agent Thereon

Examination of Longitudinal Alterations in Alzheimer’s Disease-Related Neurogenesis in an APP/PS1 Transgenic Mouse Model, and the Effects of P33, a Putative Neuroprotective Agent Thereon

Neurogenesis plays a crucial role in cognitive processes. During aging and in Alzheimer’s disease (AD), altered neurogenesis and neuroinflammation are evident both in C57BL/6J, APP<sub>Swe</sub>/PS1<sub>dE9</sub> (Tg) mice and humans. AD pathology may slow down upon drug trea...

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Bibliographic Details
Main Authors: Titanilla Szögi, Emőke Borbély, Ildikó Schuster, Zsolt Bozsó, Miklós Sántha, Melinda E. Tóth, Botond Penke, Lívia Fülöp
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:International Journal of Molecular Sciences
Subjects:
Alzheimer’s disease
neurogenesis
neuroinflammation
P33
APP/PS1 mice
Online Access:https://www.mdpi.com/1422-0067/23/18/10364

Internet

https://www.mdpi.com/1422-0067/23/18/10364

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