Detection of Caspase Activation In Situ by Fluorochrome-Labeled Caspase Inhibitors

Apoptosis is dependent on the activation of a group of proteolytic enzymes called caspases. Caspase activation can be detected by immunoblotting using caspase-specific antibodies or by caspase activity measurement employing pro-fluorescent substrates that become fluorescent upon cleavage by the casp...

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Bibliographic Details
Main Authors: P.A. Amstad, G. Yu, G.L. Johnson, B.W. Lee, S. Dhawan, D.J. Phelps
Format: Article
Language:English
Published: Taylor & Francis Group 2001-09-01
Series:BioTechniques
Online Access:https://www.future-science.com/doi/10.2144/01313pf01