Detection of Caspase Activation In Situ by Fluorochrome-Labeled Caspase Inhibitors
Apoptosis is dependent on the activation of a group of proteolytic enzymes called caspases. Caspase activation can be detected by immunoblotting using caspase-specific antibodies or by caspase activity measurement employing pro-fluorescent substrates that become fluorescent upon cleavage by the casp...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
Taylor & Francis Group
2001-09-01
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Series: | BioTechniques |
Online Access: | https://www.future-science.com/doi/10.2144/01313pf01 |