Evolution of ceftazidime-avibactam and cefiderocol resistance in ST131-H30R1-Escherichia coli isolates with KPC-3 mutants and application of FTIR biotyping

Evolution of ceftazidime-avibactam and cefiderocol resistance in ST131-H30R1-Escherichia coli isolates with KPC-3 mutants and application of FTIR biotyping

ABSTRACTCeftazidime-avibactam and cefiderocol represent two of the few alternatives for infections by KPC-producing Enterobacterales. We reported the emergence of resistance to both ceftazidime-avibactam and cefiderocol in a KPC-producing ST131-Escherichia coli (KPC-ST131-Ec) clinical isolate. Antim...

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Bibliographic Details
Main Authors: Juan Antonio Castillo-Polo, Marta Hernández-García, Ainhize Maruri-Aransolo, Carmen de la Vega, Patricia Ruiz-Garbajosa, Rafael Cantón
Format: Article
Language:English
Published: American Society for Microbiology 2024-04-01
Series:Microbiology Spectrum
Subjects:
cefiderocol resistance
ceftazidime-avibactam resistance
KPC mutants
ST131-H30R1-Escherichia coli
Online Access:https://journals.asm.org/doi/10.1128/spectrum.02776-23

Internet

https://journals.asm.org/doi/10.1128/spectrum.02776-23

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