Assessment of PD-L1 mRNA expression in gastrointestinal tumors and the response to immunotherapy

Assessment of PD-L1 mRNA expression in gastrointestinal tumors and the response to immunotherapy

BackgroundProgrammed death ligand 1 (PD-L1) immunohistochemistry (IHC) has been proposed as a predictive biomarker to predict response to immunotherapy. Given the limitations of IHC test in PD-L1 detection, this study aimed to investigate the technical feasibility of using quantitative RT-PCR (qRT-P...

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Bibliographic Details
Main Authors: Qingqing Qiu, Jieyi Li, Qiaofeng Chen, Xiaokai Zhao, Ru Zhou, Wenpeng Zhang, Ziying Gong, Daoyun Zhang, Mingliang Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-12-01
Series:Frontiers in Oncology
Subjects:
PD-L1
IHC
qRT-PCR
consistency
gastrointestinal tumors
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2022.926746/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2022.926746/full

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