Basal ganglia dopamine loss due to defect in purine recycling

Several rare inherited disorders have provided valuable experiments of nature highlighting specific biological processes of particular importance to the survival or function of midbrain dopamine neurons. In both humans and mice, deficiency of hypoxanthine-guanine phosphoribosyl transferase (HPRT) is...

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Détails bibliographiques
Auteurs principaux: Kiyoshi Egami, Silaja Yitta, Suhail Kasim, J. Chris Lewers, Rosalinda C. Roberts, Mohamed Lehar, H.A. Jinnah
Format: Article
Langue:English
Publié: Elsevier 2007-05-01
Collection:Neurobiology of Disease
Accès en ligne:http://www.sciencedirect.com/science/article/pii/S0969996107000265