Immune checkpoint blockade in hematological malignancies: current state and future potential

Malignant cells are known to evade immune surveillance by engaging immune checkpoints which are negative regulators of the immune system. By restoring the T-lymphocyte mediated anti-tumor effect, immune checkpoint inhibitors (ICI) have revolutionized the treatment of solid tumors but have met rather...

وصف كامل

التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Prateek Pophali, Juan Carlos Varela, Jacalyn Rosenblatt
التنسيق: مقال
اللغة:English
منشور في: Frontiers Media S.A. 2024-01-01
سلاسل:Frontiers in Oncology
الموضوعات:
الوصول للمادة أونلاين:https://www.frontiersin.org/articles/10.3389/fonc.2024.1323914/full