Volumetric and conductivity studies of the interaction between levocetirizine dihydrochloride and the amino acids l-alanine and l-glutamine in aqueous solutions

Levocetirizine dihydrochloride (LCTZ) is a second-generation antihistamine known for its efficacy without sedation. However, the binding mechanism with plasma protein which makes it devoid of sedative effects is yet to be uncovered. In this study, we elucidated thermodynamic parameters of solute-sol...

Full description

Bibliographic Details
Main Authors: Nur Farahani Zolkiflee, Meor Mohd Redzuan Meor Mohd Affandi, Abu Bakar Abdul Majeed
Format: Article
Language:English
Published: Elsevier 2023-04-01
Series:Heliyon
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844023015700